Use Firebug alot?  Here are some keyboard shortcuts that may come in handy.

Open/Close Firebug Panel F12
Open Firebug in a window toggle CTL + F12
Toggle inspect mode CTL + SHFT + C
Increase text size of Firebug CTL++ or CTL+ALT+Wheel UP
Decrease text size of Firebug CTL+- or CTL+ALT+Wheel Down

For a full list of Firebug Keyboard Shortcuts - Click Here